BDBM50294206 1-(1-cyclopentylphthalazin-2(1H)-yl)-3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-dimethoxyphenyl)prop-2-en-1-one::CHEMBL561644

SMILES COc1cc(Cc2cnc(N)nc2N)cc(\C=C\C(=O)N2N=Cc3ccccc3C2C2CCCC2)c1OC

InChI Key InChIKey=WKCUTOHVUOVBOV-VAWYXSNFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294206   

TargetDihydrofolate reductase(Homo sapiens (Human))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294206(1-(1-cyclopentylphthalazin-2(1H)-yl)-3-(5-((2,4-di...)
Affinity DataIC50: >2.20E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294206(1-(1-cyclopentylphthalazin-2(1H)-yl)-3-(5-((2,4-di...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of rat DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed