BDBM50294212 3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-3-methoxy-2-(2-morpholinoethoxy)phenyl)-1-(1-phenylphthalazin-2(1H)-yl)prop-2-en-1-one::CHEMBL540217

SMILES COc1cc(Cc2cnc(N)nc2N)cc(\C=C\C(=O)N2N=Cc3ccccc3C2c2ccccc2)c1OCCN1CCOCC1

InChI Key InChIKey=AJSMJPXCIPMAEN-VAWYXSNFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294212   

TargetDihydrofolate reductase(Homo sapiens (Human))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294212(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-3-methoxy...)
Affinity DataIC50: >2.10E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed