BDBM50294576 (2S,4S)-4-(((2S,3S,4R,5R)-5-(6-(2-(biphenyl-4-yl)ethylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methylthio)pyrrolidine-2-carboxylic acid::CHEMBL555257

SMILES O[C@@H]1[C@@H](CS[C@@H]2CN[C@@H](C2)C(O)=O)O[C@H]([C@@H]1O)n1cnc2c(NCCc3ccc(cc3)-c3ccccc3)ncnc12

InChI Key InChIKey=IEFYFVPAOMYINX-OGFANMSHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294576   

TargetDNA (cytosine-5)-methyltransferase 3B(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294576((2S,4S)-4-(((2S,3S,4R,5R)-5-(6-(2-(biphenyl-4-yl)e...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human recombinant DNMT3b2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50294576((2S,4S)-4-(((2S,3S,4R,5R)-5-(6-(2-(biphenyl-4-yl)e...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of human recombinant DNMT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed