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BDBM50294670 (2R,3R,4R)-2-(2-Chloro-6-(methylamino)-9H-purin-9-yl)-furan-3,4-diol::CHEMBL554275

SMILES: CNc1nc(Cl)nc2n(cnc12)[C@@H]1OC[C@@H](O)[C@H]1O

InChI Key: InChIKey=NBTBBHGGBPCDGS-NVMQTXNBSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294670   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosine receptor A3


(Homo sapiens (Human))
BDBM50294670
PNG
((2R,3R,4R)-2-(2-Chloro-6-(methylamino)-9H-purin-9-...)
Show SMILES CNc1nc(Cl)nc2n(cnc12)[C@@H]1OC[C@@H](O)[C@H]1O
Show InChI InChI=1S/C10H12ClN5O3/c1-12-7-5-8(15-10(11)14-7)16(3-13-5)9-6(18)4(17)2-19-9/h3-4,6,9,17-18H,2H2,1H3,(H,12,14,15)/t4-,6-,9-/m1/s1
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PC sid
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Similars

Article
PubMed
37.5n/an/an/an/an/an/an/an/a



Ewha Womans University

Curated by ChEMBL


Assay Description
Displacement of [3H]I-AB-MECA from human recombinant adenosine A3 receptor expressed in CHO cells by liquid scintillation counting


Bioorg Med Chem 17: 3733-8 (2009)


Article DOI: 10.1016/j.bmc.2009.03.034
BindingDB Entry DOI: 10.7270/Q2V69JMJ
More data for this
Ligand-Target Pair