BDBM50294826 1-[4-((1R,2S,6R,7S)-3,5-Dioxo-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-en-4-yl)-phenyl]-3-quinolin-8-yl-urea::CHEMBL550499

SMILES Oc1c2[C@H]3C[C@H](C=C3)c2c(O)n1-c1ccc(NC(=O)Nc2cccc3cccnc23)cc1

InChI Key InChIKey=JZHNQLJJBYEVBD-IYBDPMFKSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50294826   

TargetProto-oncogene Wnt-3(Homo sapiens (Human))
The University Of Texas Southwestern Medical Center At Dallas

Curated by ChEMBL
LigandPNGBDBM50294826(1-[4-((1R,2S,6R,7S)-3,5-Dioxo-4-aza-tricyclo[5.2.1...)
Affinity DataEC50: >2.50E+4nMAssay Description:Inhibition of Wnt3 expressed in mouse L-cells assessed as inhibition of Wnt/catanin signaling pathway by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed