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BDBM50296253 7-(6-methoxypyridin-3-yl)-3-(2-morpholinoethylamino)-1-(2-propoxyethyl)quinoxalin-2(1H)-one::CHEMBL560516

SMILES: CCCOCCn1c2cc(ccc2nc(NCCN2CCOCC2)c1=O)-c1ccc(OC)nc1

InChI Key: InChIKey=USFVOQOJWOHVLK-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296253   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (human))
BDBM50296253
PNG
(7-(6-methoxypyridin-3-yl)-3-(2-morpholinoethylamin...)
Show SMILES CCCOCCn1c2cc(ccc2nc(NCCN2CCOCC2)c1=O)-c1ccc(OC)nc1
Show InChI InChI=1S/C25H33N5O4/c1-3-13-33-16-12-30-22-17-19(20-5-7-23(32-2)27-18-20)4-6-21(22)28-24(25(30)31)26-8-9-29-10-14-34-15-11-29/h4-7,17-18H,3,8-16H2,1-2H3,(H,26,28)
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PC sid
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Similars

Article
PubMed
n/an/a 0.900n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of PDE5


Bioorg Med Chem Lett 19: 4092-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.06.004
BindingDB Entry DOI: 10.7270/Q2ZG6S9Z
More data for this
Ligand-Target Pair