BDBM50296331 (3R)-3-{[Hydroxy(di-2-thienyl)acetyl]oxy}-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane bromide::AJ-84146::Aclidinium::CHEMBL551466::Tudorza Pressair::US9333195, 44::US9687478, 44
SMILES OC(C(=O)O[C@H]1C[N+]2(CCCOc3ccccc3)CCC1CC2)(c1cccs1)c1cccs1
InChI Key InChIKey=ASMXXROZKSBQIH-VITNCHFBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50296331
Affinity DataKi: 0.0700nMAssay Description:Binding affinity to muscarinic M3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Binding affinity to muscarinic M1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Binding affinity to muscarinic M2 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Displacement of [3H]NMS from human M2R expressed in CHOK1 cell membranes incubated for 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.560nMAssay Description:Displacement of [3H]NMS from human M3R expressed in CHOK1 cell membranes incubated for 2 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:The binding of [3H]-NMS to human muscarinic receptors was performed according to Waelbroek et al (1990) (1). Assays were carried out at 25° C. Membra...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMT: 25°CAssay Description:Assays were carried out at 25° C. Membrane preparations from stably transfected chinese hamster ovary-K1 cells (CHO) expressing the genes for the...More data for this Ligand-Target Pair
Affinity DataIC50: 0.126nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Displacement of [3H]NMS from human muscarinic M4 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.140nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.170nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 0.170nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHOK1 cells by microplate scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.27E+5nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
Affinity DataIC50: 0.158nMAssay Description:Displacement of [3H]NMS from human muscarinic M5 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.126nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 16 hrs by scintillation proximity assayMore data for this Ligand-Target Pair