BDBM50296357 4,4'-(benzo[d][1,3]dioxol-5-ylazanediyl)bis(methylene)dibenzene-1,2-diol::CHEMBL551264

SMILES Oc1ccc(CN(Cc2ccc(O)c(O)c2)c2ccc3OCOc3c2)cc1O

InChI Key InChIKey=FQPNWTQWSMOJRB-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50296357   

TargetInsulin receptor(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50296357(4,4'-(benzo[d][1,3]dioxol-5-ylazanediyl)bis(methyl...)
Affinity DataIC50:  610nMAssay Description:Inhibition of human insulin receptor-mediated Poly Glu4Tyr phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50296357(4,4'-(benzo[d][1,3]dioxol-5-ylazanediyl)bis(methyl...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of IGF1R-mediated colony formation in human LNCaP cells after 12 days by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50296357(4,4'-(benzo[d][1,3]dioxol-5-ylazanediyl)bis(methyl...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of IGF1R-mediated colony formation in human MCF7 cells after 12 days by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50296357(4,4'-(benzo[d][1,3]dioxol-5-ylazanediyl)bis(methyl...)
Affinity DataIC50:  170nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50296357(4,4'-(benzo[d][1,3]dioxol-5-ylazanediyl)bis(methyl...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human IGF1R-mediated Poly Glu4Tyr phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50296357(4,4'-(benzo[d][1,3]dioxol-5-ylazanediyl)bis(methyl...)
Affinity DataIC50:  830nMAssay Description:Inhibition of human GST-fused Src-mediated Poly Glu4Tyr phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50296357(4,4'-(benzo[d][1,3]dioxol-5-ylazanediyl)bis(methyl...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of IGF1R-mediated colony formation in human PC3 cells after 12 days by MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed