BindingDB logo
myBDB logout

BDBM50296358 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid::1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid::AT-2266::CHEMBL826::CI-919::ENOXACIN::PD-107779::Penetrex::enofloxacin

SMILES: CCn1cc(C(O)=O)c(=O)c2cc(F)c(nc12)N1CCNCC1

InChI Key: InChIKey=IDYZIJYBMGIQMJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296358   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
V-type proton ATPase subunit B, brain isoform


(Homo sapiens)
BDBM50296358
PNG
(1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydr...)
Show SMILES CCn1cc(C(O)=O)c(=O)c2cc(F)c(nc12)N1CCNCC1
Show InChI InChI=1S/C15H17FN4O3/c1-2-19-8-10(15(22)23)12(21)9-7-11(16)14(18-13(9)19)20-5-3-17-4-6-20/h7-8,17H,2-6H2,1H3,(H,22,23)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



University of Florida College of Medicine

Curated by ChEMBL


Assay Description
Inhibition of maltose binding protein-fused human V-ATPase subunit B2 binding to F-actin


J Med Chem 52: 5144-51 (2010)

More data for this
Ligand-Target Pair