BDBM50296644 3-(1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-ylamino)-N-methoxy-4-methylbenzamide::CHEMBL563097

SMILES CONC(=O)c1ccc(C)c(Nc2cc(=O)n(C)c3n(ncc23)-c2ccc(F)cc2F)c1

InChI Key InChIKey=OXIJPONGRSEQAF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296644   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50296644(3-(1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihyd...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human recombinant p38alpha assessed as phosphorylation of ATF2 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed