BDBM50296743 4-bromo-3-chlorophenyl 1,4-diazabicyclo[3.2.2]nonane-4-carboxylate::CHEMBL561469

SMILES Clc1cc(OC(=O)N2CCN3CCC2CC3)ccc1Br

InChI Key InChIKey=ABBQLVQJXBDEIM-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50296743   

TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50296743(4-bromo-3-chlorophenyl 1,4-diazabicyclo[3.2.2]nona...)
Affinity DataKi:  33nMAssay Description:Displacement of [125I]BTX from rat alpha7 nAChR expressed in rat GH4C1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50296743(4-bromo-3-chlorophenyl 1,4-diazabicyclo[3.2.2]nona...)
Affinity DataIC50:  2.09E+3nMAssay Description:Displacement of [3H]epibatidine from alpha3 nAChR in human IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50296743(4-bromo-3-chlorophenyl 1,4-diazabicyclo[3.2.2]nona...)
Affinity DataIC50:  7.12E+3nMAssay Description:Displacement of L-[3H]Nicotine from alpha4beta2 nAChR in rat brain homogenate by rapid filtration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed