BDBM50297487 1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-4-(3-fluorophenyl)-3-(hydroxyimino)indolin-2-one::CHEMBL557003

SMILES Fc1cccc(c1)-c1cccc2N(Cc3cc(F)cc4COCOc34)C(=O)C(N=O)c12

InChI Key InChIKey=BDEXBHZFFRSETC-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50297487   

TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297487(1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-4...)
Affinity DataKi:  5.80E+3nMAssay Description:Inhibition of JNK3 by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297487(1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-4...)
Affinity DataKi:  7.40E+3nMAssay Description:Inhibition of p38alpha by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297487(1-((6-fluoro-4H-benzo[d][1,3]dioxin-8-yl)methyl)-4...)
Affinity DataKi:  2.30E+4nMAssay Description:Inhibition of ERK2 by spectrophotometric coupled enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed