BDBM50297797 4-(cyclohexylmethyl)-6-(6-methoxypyridin-3-yl)-2-(2-morpholinoethylamino)pyrido[2,3-b]pyrazin-3(4H)-one::CHEMBL560408

SMILES COc1ccc(cn1)-c1ccc2nc(NCCN3CCOCC3)c(=O)n(CC3CCCCC3)c2n1

InChI Key InChIKey=HOMJGWXHCJJBEQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297797   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50297797(4-(cyclohexylmethyl)-6-(6-methoxypyridin-3-yl)-2-(...)
Affinity DataIC50:  27nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50297797(4-(cyclohexylmethyl)-6-(6-methoxypyridin-3-yl)-2-(...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed