BDBM50298198 CHEMBL550673::N-((2S,3S,5R)-2-amino-6-(butylamino)-3-hydroxy-5-methyl-6-oxohexyl)-4-bromo-N-isopropyl-3-(3-methoxypropoxy)benzamide

SMILES CCCCNC(=O)[C@H](C)C[C@H](O)[C@@H](N)CN(C(C)C)C(=O)c1ccc(Br)c(OCCCOC)c1

InChI Key InChIKey=FLYYEPGUPIYISO-COPCDDAFSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50298198   

TargetRenin(Homo sapiens (Human))
Nagasaki International University

Curated by ChEMBL
LigandPNGBDBM50298198(CHEMBL550673 | N-((2S,3S,5R)-2-amino-6-(butylamino...)
Affinity DataIC50:  8nMAssay Description:Inhibition of purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Rattus norvegicus)
Nagasaki International University

Curated by ChEMBL
LigandPNGBDBM50298198(CHEMBL550673 | N-((2S,3S,5R)-2-amino-6-(butylamino...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of rat reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
Nagasaki International University

Curated by ChEMBL
LigandPNGBDBM50298198(CHEMBL550673 | N-((2S,3S,5R)-2-amino-6-(butylamino...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of bovine cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Nagasaki International University

Curated by ChEMBL
LigandPNGBDBM50298198(CHEMBL550673 | N-((2S,3S,5R)-2-amino-6-(butylamino...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed