BDBM50298199 CHEMBL561342::N-((2S,3S,5R)-2-amino-6-(butylamino)-3-hydroxy-5-methyl-6-oxohexyl)-4-ethynyl-N-isopropyl-3-(3-methoxypropoxy)benzamide

SMILES CCCCNC(=O)[C@H](C)C[C@H](O)[C@@H](N)CN(C(C)C)C(=O)c1ccc(C#C)c(OCCCOC)c1

InChI Key InChIKey=ODNZUSLIDNYDNQ-QDSKXPNFSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50298199   

TargetRenin(Homo sapiens (Human))
Nagasaki International University

Curated by ChEMBL
LigandPNGBDBM50298199(CHEMBL561342 | N-((2S,3S,5R)-2-amino-6-(butylamino...)
Affinity DataIC50:  6nMAssay Description:Inhibition of purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
Nagasaki International University

Curated by ChEMBL
LigandPNGBDBM50298199(CHEMBL561342 | N-((2S,3S,5R)-2-amino-6-(butylamino...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of bovine cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Nagasaki International University

Curated by ChEMBL
LigandPNGBDBM50298199(CHEMBL561342 | N-((2S,3S,5R)-2-amino-6-(butylamino...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed