BDBM50298823 (S)-5-(3-(3'-tert-butyl-5-methoxybiphenyl-3-yl)but-1-ynyl)-6-methylpyrimidine-2,4-diamine::CHEMBL578648

SMILES COc1cc(cc(c1)-c1ccc(cc1)C(C)(C)C)[C@H](C)C#Cc1c(C)nc(N)nc1N

InChI Key InChIKey=AOJOORYEHDDWCH-MRXNPFEDSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50298823   

TargetDihydrofolate reductase(Candida albicans)
University Of Connecticut

Curated by ChEMBL
LigandPNGBDBM50298823((S)-5-(3-(3'-tert-butyl-5-methoxybiphenyl-3-yl)but...)
Affinity DataIC50:  34nMAssay Description:Inhibition of Candida albicans DHFR expressed in Escherichia coli BL21 (DE3) assessed as rate of NADPH consumption using dihydrofolate as susbtrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed