BDBM50299064 2-(Biphenyl-4-ylsulfonyl)N-hydroxybenzamide::CHEMBL574589

SMILES ONC(=O)c1ccccc1S(=O)(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=WQRJSSRVHCJAKB-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50299064   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299064(2-(Biphenyl-4-ylsulfonyl)N-hydroxybenzamide | CHEM...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP9 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299064(2-(Biphenyl-4-ylsulfonyl)N-hydroxybenzamide | CHEM...)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of human recombinant pro-MMP14 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299064(2-(Biphenyl-4-ylsulfonyl)N-hydroxybenzamide | CHEM...)
Affinity DataIC50:  590nMAssay Description:Inhibition of autoactivated human pro-MMP12 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299064(2-(Biphenyl-4-ylsulfonyl)N-hydroxybenzamide | CHEM...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP8 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299064(2-(Biphenyl-4-ylsulfonyl)N-hydroxybenzamide | CHEM...)
Affinity DataIC50:  7.30E+4nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP1 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299064(2-(Biphenyl-4-ylsulfonyl)N-hydroxybenzamide | CHEM...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP13 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299064(2-(Biphenyl-4-ylsulfonyl)N-hydroxybenzamide | CHEM...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299064(2-(Biphenyl-4-ylsulfonyl)N-hydroxybenzamide | CHEM...)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibition of trypsin activated human pro-MMP3 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299064(2-(Biphenyl-4-ylsulfonyl)N-hydroxybenzamide | CHEM...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP2 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed