BDBM50299068 CHEMBL575895::N-Hydroxy-2-(4-methoxy-benzenesulfonyl)benzamide

SMILES COc1ccc(cc1)S(=O)(=O)c1ccccc1C(=O)NO

InChI Key InChIKey=QPFIKHZWPMXTRS-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50299068   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299068(CHEMBL575895 | N-Hydroxy-2-(4-methoxy-benzenesulfo...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP9 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299068(CHEMBL575895 | N-Hydroxy-2-(4-methoxy-benzenesulfo...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of human recombinant pro-MMP14 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299068(CHEMBL575895 | N-Hydroxy-2-(4-methoxy-benzenesulfo...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of autoactivated human pro-MMP12 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299068(CHEMBL575895 | N-Hydroxy-2-(4-methoxy-benzenesulfo...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP13 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299068(CHEMBL575895 | N-Hydroxy-2-(4-methoxy-benzenesulfo...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of trypsin activated human pro-MMP3 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299068(CHEMBL575895 | N-Hydroxy-2-(4-methoxy-benzenesulfo...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP2 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299068(CHEMBL575895 | N-Hydroxy-2-(4-methoxy-benzenesulfo...)
Affinity DataIC50:  7.20E+4nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP8 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299068(CHEMBL575895 | N-Hydroxy-2-(4-methoxy-benzenesulfo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP1 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50299068(CHEMBL575895 | N-Hydroxy-2-(4-methoxy-benzenesulfo...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed