BDBM50299209 (5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-11-benzyl-8-(naphthalen-2-ylmethyl)-7,10,13-trioxo-1,3-dithia-6,9,12-triazacyclopentadecane-5-carboxamide::CHEMBL572525

SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CSCSC[C@H](NC(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2ccccc2)NC1=O)C(N)=O

InChI Key InChIKey=FWDMWCQXNFZSCZ-PMUGGPHNSA-N

Data  4 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50299209   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299209((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  0.470nMAssay Description:Displacement of [3H]diprenorphine from rat mu opioid receptor expressed in rat C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299209((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  0.480nMAssay Description:Displacement of [3H]diprenorphine from rat delta opioid receptor expressed in rat C6 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299209((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299209((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity to rat delta opioid receptor expressed in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299209((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataEC50:  36nMAssay Description:Agonist activity at rat delta opioid receptor expressed in rat C6 cells assessed as inhibition of forskolin-stimulated cAMP production after 30 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299209((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding after 1 hr by liquid scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50299209((5R,8S,11S,14S)-14-((S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at rat mu opioid receptor expressed in rat C6 cells assessed as stimulation of [35S]GTPgammaS binding after 1 hr by liquid scintilla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed