BDBM50299250 7-(2,4-Difluorophenyl)-1,10-dihydropyrrolo[2,3-a]carbazole-3-carbaldehyde::CHEMBL575739::US8481586, 40

SMILES Fc1ccc(c(F)c1)-c1ccc2[nH]c3c(ccc4c(C=O)c[nH]c34)c2c1

InChI Key InChIKey=BFWHRHJPPAUSLJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50299250   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50299250(7-(2,4-Difluorophenyl)-1,10-dihydropyrrolo[2,3-a]c...)
Affinity DataIC50:  660nMAssay Description:Inhibition assay using PIM-1, PIM-2 and PIM-3.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Centre National De La Recherche Scientifique

US Patent
LigandPNGBDBM50299250(7-(2,4-Difluorophenyl)-1,10-dihydropyrrolo[2,3-a]c...)
Affinity DataIC50:  660nMAssay Description:Inhibition of Pim-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50299250(7-(2,4-Difluorophenyl)-1,10-dihydropyrrolo[2,3-a]c...)
Affinity DataIC50:  200nMAssay Description:Inhibition of Pim-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50299250(7-(2,4-Difluorophenyl)-1,10-dihydropyrrolo[2,3-a]c...)
Affinity DataIC50:  200nMAssay Description:Inhibition assay using PIM-1, PIM-2 and PIM-3.More data for this Ligand-Target Pair
In DepthDetails US Patent