BDBM50299821 (+/-)-syn-7-(4-Bromophenyl)-6-(4-chlorophenyl)-12-methyl-7,12-dihydro-6H-chromeno[4,3-d][1,2,4]triazolo[1,5-a]pyrimidine::CHEMBL567636

SMILES CN1c2ncnn2C(C2=C1c1ccccc1OC2c1ccc(Cl)cc1)c1ccc(Br)cc1

InChI Key InChIKey=PQGSGKGNJOWFEG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50299821   

TargetCellular tumor antigen p53(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50299821((+/-)-syn-7-(4-Bromophenyl)-6-(4-chlorophenyl)-12-...)
Affinity DataIC50:  1.50E+4nMAssay Description:Induction of p53 in human HCT116 cells coexpressing pp53TA-luc assessed as inhibition of cell proliferation after 8 hrs by firefly/renilla luciferase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed