BDBM50299849 1-(3,4-Dimethoxyphenyl)-3-(3-(4-methyl-1H-imidazol-1-yl)propyl)thiourea::CHEMBL565917::US9656991, 8

SMILES COc1ccc(NC(=S)NCCCn2cnc(C)c2)cc1OC

InChI Key InChIKey=WBMNLCQLBFBMPR-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299849   

TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM50299849(1-(3,4-Dimethoxyphenyl)-3-(3-(4-methyl-1H-imidazol...)
Affinity DataKi:  60nMAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM50299849(1-(3,4-Dimethoxyphenyl)-3-(3-(4-methyl-1H-imidazol...)
Affinity DataKi:  60nMAssay Description:Inhibition of human glutaminyl cyclase expressed in Pichia pastoris by pGAP coupled enzyme assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed