BDBM50300186 CHEMBL583302::N-[5-benzylamino-1S-(3,5-difluoro-phenoxymethyl)-2R-hydroxy-4R-methoxy-pentyl]-5-(methanesulfonyl-methyl-amino)-N'-(1R-phenyl-ethyl)-isophthalamide

SMILES CO[C@@H](CNCc1ccccc1)C[C@@H](O)[C@H](COc1cc(F)cc(F)c1)NC(=O)c1cc(cc(c1)C(=O)N[C@H](C)c1ccccc1)N(C)S(C)(=O)=O

InChI Key InChIKey=RVLBBCQVPOSNBV-BBFZAZMFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50300186   

TargetBeta-secretase 1(Homo sapiens (Human))
Stockholm University

Curated by ChEMBL
LigandPNGBDBM50300186(CHEMBL583302 | N-[5-benzylamino-1S-(3,5-difluoro-p...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human brain BACE1 expressed in Escherichia coli BL21(DE) by TRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed