BDBM50300575 (R)-2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)amino)butoxy)phenyl)acetic acid::CHEMBL573677

SMILES C[C@H](CCOc1cccc(CC(O)=O)c1)N(CC(c1ccccc1)c1ccccc1)Cc1cccc(c1Cl)C(F)(F)F

InChI Key InChIKey=ZLJZDYOBXVOTSA-XMMPIXPASA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300575   

TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50300575((R)-2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to PXR by scintillation proximity binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50300575((R)-2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human LXRbeta assessed as association of SRC1 to LXRbeta ligand binding domain by FRET based cell-free ligand sensing assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50300575((R)-2-(3-(3-((2-chloro-3-(trifluoromethyl)benzyl)(...)
Affinity DataEC50:  74nMAssay Description:Agonist activity at human LXRalpha assessed as association of SRC1 to LXRalpha ligand binding domain by FRET based cell-free ligand sensing assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed