BDBM50301192 6-((4-(fluoromethyl)-5-methylthiazol-2-ylthio)methyl)-N-((6-methylpyridin-2-yl)methyl)-4-morpholinopyridin-2-amine::CHEMBL585711

SMILES Cc1sc(SCc2cc(cc(NCc3cccc(C)n3)n2)N2CCOCC2)nc1CF

InChI Key InChIKey=BHHGCAUKPABREW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50301192   

TargetNeuropeptide Y receptor type 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301192(6-((4-(fluoromethyl)-5-methylthiazol-2-ylthio)meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]-PYY from human NPYY2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301192(6-((4-(fluoromethyl)-5-methylthiazol-2-ylthio)meth...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [125I]-PYY from human NPYY1 receptor overexpressed in CHO cell membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301192(6-((4-(fluoromethyl)-5-methylthiazol-2-ylthio)meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]-PYY from human NPYY5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 4(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50301192(6-((4-(fluoromethyl)-5-methylthiazol-2-ylthio)meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [125I]-PYY from human NPYY4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed