BDBM50301984 2-(6-(3'-(aminomethyl)biphenyl-3-yloxy)-3,5-difluoro-4-(piperazin-1-yl)pyridin-2-yloxy)-4-(dimethylamino)benzoic acid::CHEMBL572022

SMILES CN(C)c1ccc(C(O)=O)c(Oc2nc(Oc3cccc(c3)-c3cccc(CN)c3)c(F)c(N3CCNCC3)c2F)c1

InChI Key InChIKey=VIWAMLXNVNUQII-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50301984   

TargetPlasminogen(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50301984(2-(6-(3'-(aminomethyl)biphenyl-3-yloxy)-3,5-difluo...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50301984(2-(6-(3'-(aminomethyl)biphenyl-3-yloxy)-3,5-difluo...)
Affinity DataIC50:  65nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Berlex Biosciences

Curated by ChEMBL
LigandPNGBDBM50301984(2-(6-(3'-(aminomethyl)biphenyl-3-yloxy)-3,5-difluo...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of tPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed