BDBM50302108 CHEMBL569445::Grassystatin C

SMILES CC[C@H](C)[C@@H](O)C(=O)N[C@@H](CC(C)C)C(=O)N(C)[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)[C@@H](O)CC(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N(C)[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)OC

InChI Key InChIKey=CRTPOZWNLFMWPB-YQGVOMCUSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50302108   

TargetCathepsin D(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50302108(CHEMBL569445 | Grassystatin C)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin E(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50302108(CHEMBL569445 | Grassystatin C)
Affinity DataIC50:  43nMAssay Description:Inhibition of cathepsin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50302108(CHEMBL569445 | Grassystatin C)
Affinity DataIC50:  2.86E+4nMAssay Description:Inhibition of TACE after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50302108(CHEMBL569445 | Grassystatin C)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAM10 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 9(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50302108(CHEMBL569445 | Grassystatin C)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ADAM9 after 10 to 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed