BDBM50302421 2-(6-(2-cyclopropylethoxy)-9-(2-hydroxy-2-methylpropyl)-1H-phenanthro[9,10-d]imidazol-2-yl)-5-fluoroisophthalonitrile::CHEMBL565406
SMILES CC(C)(O)Cc1ccc2c3nc([nH]c3c3ccc(OCCC4CC4)cc3c2c1)-c1c(cc(F)cc1C#N)C#N
InChI Key InChIKey=PYRKKGOKRMZEIT-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50302421
Affinity DataIC50: 1nMAssay Description:Inhibition of mPGES-1 in IL-1beta-stimulated human A549 cell microsomal membranes assessed as reduction in PGE2 formation incubated for 15 mins using...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]PGH2 from human recombinant PGES1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
TargetThromboxane-A synthase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of TX synthaseMore data for this Ligand-Target Pair
TargetProstaglandin E synthase 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human PGES2More data for this Ligand-Target Pair