BDBM50302618 (2S,3R,4R,5S)-2-(4'-Ethoxybiphenyl-4-yl)-6-methoxytetrahydro-2H-pyran-3,4,5-triol::CHEMBL567777

SMILES CCOc1ccc(cc1)-c1cccc(c1)[C@@H]1OC(OC)[C@@H](O)[C@H](O)[C@H]1O

InChI Key InChIKey=KQVVKGCCRNPRJA-WYGKVCCSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50302618   

TargetSodium/glucose cotransporter 2(Mus musculus (Mouse))
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302618((2S,3R,4R,5S)-2-(4'-Ethoxybiphenyl-4-yl)-6-methoxy...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302618((2S,3R,4R,5S)-2-(4'-Ethoxybiphenyl-4-yl)-6-methoxy...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as inhibition of [14C]alpha-methylglucopyranoside uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed