BDBM50302900 7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methylthio)quinoline::CHEMBL567089

SMILES COc1ccc2c(SCc3nnc4ccc(nn34)-c3ccccc3)ccnc2c1

InChI Key InChIKey=LSZYMWXOOBDCEC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50302900   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50302900(7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyrid...)
Affinity DataIC50: >6.67E+3nMAssay Description:Inhibition of c-Met by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50302900(7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyrid...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human CYP3A4 in human liver microsomes preincubated with NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50302900(7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyrid...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed