BDBM50303262 CHEMBL566010::N1-(3-fluoro-4-(2-(pyrrolidine-1-carbonyl)thieno[3,2-b]pyridin-7-yloxy)phenyl)-N3-phenylmalonamide

SMILES Fc1cc(NC(=O)CC(=O)Nc2ccccc2)ccc1Oc1ccnc2cc(sc12)C(=O)N1CCCC1

InChI Key InChIKey=QMEPZWHCBROEIB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50303262   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50303262(CHEMBL566010 | N1-(3-fluoro-4-(2-(pyrrolidine-1-ca...)
Affinity DataIC50:  4nMAssay Description:Inhibition of GST-fused recombinant VEGFR2 expressed in baculovirus infected Sf9 cells after 10 mins by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50303262(CHEMBL566010 | N1-(3-fluoro-4-(2-(pyrrolidine-1-ca...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of TPR-met autophosphorylation expressed in HEK293T cells after 150 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50303262(CHEMBL566010 | N1-(3-fluoro-4-(2-(pyrrolidine-1-ca...)
Affinity DataIC50:  40nMAssay Description:Inhibition of GST-fused recombinant C-met expressed in baculovirus infected high five cells after 30 mins by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed