BDBM50303763 (R)-2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido)-3-methylbutanoic acid::CHEMBL568873
SMILES CC(C)[C@@H](NC(=O)c1nc(Cl)c2ccccc2c1O)C(O)=O
InChI Key InChIKey=BNYWBSPWOHMZNE-SNVBAGLBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50303763
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of human PHD2 at 293K temperature by solvent relaxation techniqueMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...More data for this Ligand-Target Pair
Affinity DataKd: 3.30E+4nMAssay Description:Binding affinity to human PHD2 by nondenaturing ESI-MSMore data for this Ligand-Target Pair
Affinity DataKd: 3.30E+4nMAssay Description:Binding affinity to human PHD2-Mn(II) using 12.5% H2O/87.5% D2O MQC spectrometer operated at 500 MHz at 298K temperatureMore data for this Ligand-Target Pair