BDBM50303906 (E)-4-(isopropylimino)-2-methylnaphthalen-1(4H)-one::CHEMBL576123

SMILES CC(C)N=C1C=C(C)C(=O)c2ccccc12

InChI Key InChIKey=RDPKFQFAMQRHBW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50303906   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303906((E)-4-(isopropylimino)-2-methylnaphthalen-1(4H)-on...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant IDO expressed in HEK293 cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303906((E)-4-(isopropylimino)-2-methylnaphthalen-1(4H)-on...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of mouse recombinant IDO expressed in mouse P815B cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303906((E)-4-(isopropylimino)-2-methylnaphthalen-1(4H)-on...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant IDO expressed in Escherichia coli BL21 AIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 2,3-dioxygenase(Mus musculus)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303906((E)-4-(isopropylimino)-2-methylnaphthalen-1(4H)-on...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of mouse recombinant TDO expressed in mouse P815B cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed