BDBM50303910 4-phenylthiazole-2-thiol::CHEMBL571436

SMILES Sc1nc(cs1)-c1ccccc1

InChI Key InChIKey=CYCKHTAVNBPQDB-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50303910   

TargetTryptophan 2,3-dioxygenase(Mus musculus)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303910(4-phenylthiazole-2-thiol | CHEMBL571436)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of mouse recombinant TDO expressed in mouse P815B cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303910(4-phenylthiazole-2-thiol | CHEMBL571436)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human recombinant IDO expressed in Escherichia coli BL21 AIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303910(4-phenylthiazole-2-thiol | CHEMBL571436)
Affinity DataIC50:  2.44E+4nMAssay Description:Inhibition of human IDO1 pre-incubated for 10 mins before L-Trp as substrate addition and measured after 30 mins by colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303910(4-phenylthiazole-2-thiol | CHEMBL571436)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human recombinant IDO expressed in HEK293 cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303910(4-phenylthiazole-2-thiol | CHEMBL571436)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of human IDO1 pre-incubated for 10 mins before L-Trp as substrate addition and measured after 30 mins by colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
Institute For Cancer Research

Curated by ChEMBL
LigandPNGBDBM50303910(4-phenylthiazole-2-thiol | CHEMBL571436)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of mouse recombinant IDO expressed in mouse P815B cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed