BDBM50303910 4-phenylthiazole-2-thiol::CHEMBL571436
SMILES Sc1nc(cs1)-c1ccccc1
InChI Key InChIKey=CYCKHTAVNBPQDB-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50303910
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of mouse recombinant TDO expressed in mouse P815B cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Institute For Cancer Research
Curated by ChEMBL
Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant IDO expressed in Escherichia coli BL21 AIMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Institute For Cancer Research
Curated by ChEMBL
Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 2.44E+4nMAssay Description:Inhibition of human IDO1 pre-incubated for 10 mins before L-Trp as substrate addition and measured after 30 mins by colorimetryMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Institute For Cancer Research
Curated by ChEMBL
Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant IDO expressed in HEK293 cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Institute For Cancer Research
Curated by ChEMBL
Institute For Cancer Research
Curated by ChEMBL
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human IDO1 pre-incubated for 10 mins before L-Trp as substrate addition and measured after 30 mins by colorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse recombinant IDO expressed in mouse P815B cells assessed as blockade of tryptophan degradation by HPLCMore data for this Ligand-Target Pair