BDBM50304367 CHEMBL595786::N-(4-(N-(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl)phenyl)naphthalene-2-sulfonamide::US9320734, 455

SMILES Cc1nnc(NS(=O)(=O)c2ccc(NS(=O)(=O)c3ccc4ccccc4c3)cc2)s1

InChI Key InChIKey=YHFXJWRRQDJXOA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304367   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
The University Of Texas

Curated by ChEMBL
LigandPNGBDBM50304367(CHEMBL595786 | N-(4-(N-(5-methyl-1,3,4-thiadiazol-...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of pleckstrin homology domain of AKT by surface plasmon resonance spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase [1-123](Homo sapiens (Human))
The University Of Texas System

US Patent
LigandPNGBDBM50304367(CHEMBL595786 | N-(4-(N-(5-methyl-1,3,4-thiadiazol-...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of AKT was measured by Western blotting using specific antibodies against phospho-Ser473-AKT in MiaPaCa-2 cells.Inhibition of AKT was meas...More data for this Ligand-Target Pair
In DepthDetails US Patent