BDBM50304511 6-ethyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyrimidine::CHEMBL594730

SMILES CCc1cc2c(ncnc2s1)N1CCN(C)CC1

InChI Key InChIKey=ZAYUCMVNISSUTM-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304511   

TargetHistamine H4 receptor(Homo sapiens (Human))
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50304511(6-ethyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyr...)
Affinity DataKi:  6.60E+3nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai2 and Gbeta1gamma2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM50304511(6-ethyl-4-(4-methylpiperazin-1-yl)thieno[2,3-d]pyr...)
Affinity DataIC50:  1.70E+5nMAssay Description:Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...More data for this Ligand-Target Pair
In DepthDetails US Patent