BDBM50304786 CHEMBL603422::methyl 4-(3-chloro-4-methoxybenzylamino)-8-(2-hydroxyethyl)-7-methoxyquinazolin-6-ylcarbamate

SMILES COC(=O)Nc1cc2c(NCc3ccc(OC)c(Cl)c3)ncnc2c(CCO)c1OC

InChI Key InChIKey=GOALVSVFDUWXLQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50304786   

TargetRod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha(Bos taurus (Bovine))
Chong Kun Dang Research Institute

Curated by ChEMBL
LigandPNGBDBM50304786(CHEMBL603422 | methyl 4-(3-chloro-4-methoxybenzyla...)
Affinity DataIC50:  710nMAssay Description:Inhibition of bovine retina PDE6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bos taurus)
Chong Kun Dang Research Institute

Curated by ChEMBL
LigandPNGBDBM50304786(CHEMBL603422 | methyl 4-(3-chloro-4-methoxybenzyla...)
Affinity DataIC50:  3nMAssay Description:Inhibition of bovine platelet PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed