BDBM50305300 3-(6-morpholino-9-(piperidin-4-yl)-9H-purin-2-yl)phenol::CHEMBL593768

SMILES Oc1cccc(c1)-c1nc(N2CCOCC2)c2ncn(C3CCNCC3)c2n1

InChI Key InChIKey=ZNNJFEULXHWOFQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50305300   

LigandPNGBDBM50305300(3-(6-morpholino-9-(piperidin-4-yl)-9H-purin-2-yl)p...)
Affinity DataIC50:  64nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305300(3-(6-morpholino-9-(piperidin-4-yl)-9H-purin-2-yl)p...)
Affinity DataIC50:  133nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305300(3-(6-morpholino-9-(piperidin-4-yl)-9H-purin-2-yl)p...)
Affinity DataIC50:  870nMAssay Description:Inhibition of human TOR in HEK293 cells by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305300(3-(6-morpholino-9-(piperidin-4-yl)-9H-purin-2-yl)p...)
Affinity DataIC50:  65nMAssay Description:Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50305300(3-(6-morpholino-9-(piperidin-4-yl)-9H-purin-2-yl)p...)
Affinity DataIC50:  131nMAssay Description:Inhibition of GST-GRP1-fused PI3Kgamma by microtiter plate based fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305300(3-(6-morpholino-9-(piperidin-4-yl)-9H-purin-2-yl)p...)
Affinity DataIC50:  950nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed