BDBM50305376 3-(3-Trifluoromethyl-phenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)-propenone::CHEMBL590134

SMILES Cc1nn(C(=O)\C=C\c2cccc(c2)C(F)(F)F)c2C[C@@H]3[C@H](c12)C3(C)C

InChI Key InChIKey=RAEXFDVJMFJGFO-WXVPVVBVSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50305376   

TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50305376(3-(3-Trifluoromethyl-phenyl)-1-((3bS,4aR)-3,4,4-tr...)
Affinity DataEC50:  26nMAssay Description:Agonist activity at human SIP1 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50305376(3-(3-Trifluoromethyl-phenyl)-1-((3bS,4aR)-3,4,4-tr...)
Affinity DataEC50:  325nMAssay Description:Agonist activity at human SIP5 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50305376(3-(3-Trifluoromethyl-phenyl)-1-((3bS,4aR)-3,4,4-tr...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human SIP4 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50305376(3-(3-Trifluoromethyl-phenyl)-1-((3bS,4aR)-3,4,4-tr...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human SIP3 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed