BDBM50305481 2-amino-4-cyclohexyl-4-phenyl-1-((tetrahydrofuran-2-yl)methyl)-1H-imidazol-5(4H)-one::CHEMBL592534

SMILES NC1=NC(C2CCCCC2)(C(=O)N1CC1CCCO1)c1ccccc1

InChI Key InChIKey=DWDSPZQJZVOFAW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305481   

TargetBeta-secretase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305481(2-amino-4-cyclohexyl-4-phenyl-1-((tetrahydrofuran-...)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305481(2-amino-4-cyclohexyl-4-phenyl-1-((tetrahydrofuran-...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human BACE2 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-secretase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305481(2-amino-4-cyclohexyl-4-phenyl-1-((tetrahydrofuran-...)
Affinity DataIC50:  1.04E+3nMAssay Description:Inhibition of human BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed