BDBM50305742 CHEMBL605416::N,N'-(propane-1,3-diyl)bis(4-methyl-N-phenylbenzenesulfonamide)

SMILES Cc1ccc(cc1)S(=O)(=O)N(CCCN(c1ccccc1)S(=O)(=O)c1ccc(C)cc1)c1ccccc1

InChI Key InChIKey=SGVPWBUQRZBOIF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50305742   

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305742(CHEMBL605416 | N,N'-(propane-1,3-diyl)bis(4-methyl...)
Affinity DataIC50: >6.00E+4nMAssay Description:Antagonist activity at human C5a receptor expressed in CHO cells co-expressed with Galpha16 assessed as inhibition of anaphylatoxin C5a-induced intra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305742(CHEMBL605416 | N,N'-(propane-1,3-diyl)bis(4-methyl...)
Affinity DataIC50: >6.00E+4nMAssay Description:Antagonist activity at C5a receptor in human PMNC assessed as inhibition of anaphylatoxin C5a-induced intracellular calcium accumulation after 10 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed