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BDBM50306360 5-(4-(2,4-dimethylphenoxy)benzyl)thiazolidine-2,4-dione::CHEMBL599280

SMILES: Cc1ccc(Oc2ccc(Cc3sc(=O)[nH]c3O)cc2)c(C)c1

InChI Key: InChIKey=IOKVZBISAQZMTJ-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306360   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Free fatty acid receptor 1


(Homo sapiens (human))
BDBM50306360
PNG
(5-(4-(2,4-dimethylphenoxy)benzyl)thiazolidine-2,4-...)
Show SMILES Cc1ccc(Oc2ccc(Cc3sc(=O)[nH]c3O)cc2)c(C)c1
Show InChI InChI=1S/C18H17NO3S/c1-11-3-8-15(12(2)9-11)22-14-6-4-13(5-7-14)10-16-17(20)19-18(21)23-16/h3-9,20H,10H2,1-2H3,(H,19,21)
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Similars

Article
PubMed
n/an/an/an/a 121n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human GPR40 by FLIPR assay in presence of 1% BSA


Bioorg Med Chem Lett 20: 1298-301 (2010)

More data for this
Ligand-Target Pair