BDBM50307091 4-Nitrophenyl 2,2-Diphenyl-1-oxa-6-azaspiro[2.5]octane-6-carboxylate::CHEMBL603077

SMILES [O-][N+](=O)c1ccc(OC(=O)N2CCC3(CC2)OC3(c2ccccc2)c2ccccc2)cc1

InChI Key InChIKey=XLSYJZPQBBHHPO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50307091   

TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50307091(4-Nitrophenyl 2,2-Diphenyl-1-oxa-6-azaspiro[2.5]oc...)
Affinity DataIC50:  5.85E+3nMAssay Description:Inhibition of FAAH in mouse brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50307091(4-Nitrophenyl 2,2-Diphenyl-1-oxa-6-azaspiro[2.5]oc...)
Affinity DataIC50:  380nMAssay Description:Inhibition of ABHD6 in mouse brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50307091(4-Nitrophenyl 2,2-Diphenyl-1-oxa-6-azaspiro[2.5]oc...)
Affinity DataIC50:  200nMAssay Description:Inhibition of MAGL in mouse brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed