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BDBM50307812 1-[3-(4-Bromo-2-methyl-2Hpyrazol-3-yl)-4-methoxyphenyl]-3-(4-chlorophenyl)urea::CHEMBL591223

SMILES: COc1ccc(NC(=O)Nc2ccc(Cl)cc2)cc1-c1c(Br)cnn1C

InChI Key: InChIKey=OLSNXEOXWIBURX-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50307812   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))
BDBM50307812
PNG
(1-[3-(4-Bromo-2-methyl-2Hpyrazol-3-yl)-4-methoxyph...)
Show SMILES COc1ccc(NC(=O)Nc2ccc(Cl)cc2)cc1-c1c(Br)cnn1C
Show InChI InChI=1S/C18H16BrClN4O2/c1-24-17(15(19)10-21-24)14-9-13(7-8-16(14)26-2)23-18(25)22-12-5-3-11(20)4-6-12/h3-10H,1-2H3,(H2,22,23,25)
MMDB

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Similars

Article
PubMed
n/an/an/an/a 0.700n/an/an/an/a



Arena Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Activity at human 5HT2A receptor expressed in HEK293 cells assessed as [3H]inositol phosphate production by scintillation counting


J Med Chem 53: 1923-36 (2010)


Article DOI: 10.1021/jm9007328
BindingDB Entry DOI: 10.7270/Q24B31FP
More data for this
Ligand-Target Pair