BDBM50308358 (Z)-5-(2-fluorobenzylidene)thiazolidine-2,4-dione::CHEMBL601199

SMILES Fc1ccccc1\C=C1/SC(=O)NC1=O

InChI Key InChIKey=HWSHSFNYTZXIGL-YVMONPNESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50308358   

TargetInsulin receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50308358((Z)-5-(2-fluorobenzylidene)thiazolidine-2,4-dione ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of IR by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGlycogen synthase kinase-3 beta(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50308358((Z)-5-(2-fluorobenzylidene)thiazolidine-2,4-dione ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of GSK3beta (unknown origin) using GS-2 peptide substrate incubated for 30 mins by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInsulin-like growth factor 1 receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50308358((Z)-5-(2-fluorobenzylidene)thiazolidine-2,4-dione ...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of IGF1R by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed