BDBM50308559 3-((1R,4R)-2,5-diazabicyclo[2.2.1]heptan-2-yl)-1-(2-propoxyethyl)-7-(6-methoxypyridin-3-yl)pyrido[3,4-b]pyrazin-2(1H)-one::CHEMBL602120

SMILES CCCOCCn1c2cc(ncc2nc(N2C[C@H]3C[C@@H]2CN3)c1=O)-c1ccc(OC)nc1

InChI Key InChIKey=QDIQYFQPTWVPLK-IAGOWNOFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50308559   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50308559(3-((1R,4R)-2,5-diazabicyclo[2.2.1]heptan-2-yl)-1-(...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human platelet PDE5 assessed as reduction in conversion of [3H]cGMP to [3H]GMP after 2 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed