BDBM50309191 2-Amino-N-(2-aminoethyl)-5-(2,3-dihydrothieno[3,4-b][1,4]dioxin-5-yl)nicotinamide::CHEMBL599171

SMILES NCCNC(=O)c1cc(cnc1N)-c1scc2OCCOc12

InChI Key InChIKey=RSXFSSZTSZFLPI-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50309191   

TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309191(2-Amino-N-(2-aminoethyl)-5-(2,3-dihydrothieno[3,4-...)
Affinity DataIC50:  28nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309191(2-Amino-N-(2-aminoethyl)-5-(2,3-dihydrothieno[3,4-...)
Affinity DataEC50:  5.00E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309191(2-Amino-N-(2-aminoethyl)-5-(2,3-dihydrothieno[3,4-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed