BDBM50309269 2-(2-(biphenyl-2-ylmethyl)-4-(4-chlorophenyl)thiazol-5-yl)acetic acid::CHEMBL607423

SMILES OC(=O)Cc1sc(Cc2ccccc2-c2ccccc2)nc1-c1ccc(Cl)cc1

InChI Key InChIKey=XSEQEOCIQGGXMC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50309269   

TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50309269(2-(2-(biphenyl-2-ylmethyl)-4-(4-chlorophenyl)thiaz...)
Affinity DataIC50:  510nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in HEK285-7 cells assessed as inhibition of beta arrestin translocation by bioluminescence reso...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50309269(2-(2-(biphenyl-2-ylmethyl)-4-(4-chlorophenyl)thiaz...)
Affinity DataIC50:  41nMAssay Description:Displacement of[3H]PGD2 from human CRTH2 receptor expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50309269(2-(2-(biphenyl-2-ylmethyl)-4-(4-chlorophenyl)thiaz...)
Affinity DataIC50:  510nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in HEK285-7 cells assessed as inhibition of beta arrestin translocation by bioluminescence reso...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50309269(2-(2-(biphenyl-2-ylmethyl)-4-(4-chlorophenyl)thiaz...)
Affinity DataIC50:  41nMAssay Description:Displacement of[3H]PGD2 from human CRTH2 receptor expressed in HEK385-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed