BDBM50309336 9-methyl-3,4,4a,5-tetrahydro-1H-pyrazino[1,2-a]quinazolin-6(2H)-one::CHEMBL590331

SMILES Cc1ccc2C(=O)NC3CNCCN3c2c1

InChI Key InChIKey=NJFUCAPBXYJVNU-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50309336   

Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309336(9-methyl-3,4,4a,5-tetrahydro-1H-pyrazino[1,2-a]qui...)
Affinity DataKi:  280nMAssay Description:Displacement of [125I]LSD from human recombinant 5HT2B receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309336(9-methyl-3,4,4a,5-tetrahydro-1H-pyrazino[1,2-a]qui...)
Affinity DataKi:  479nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309336(9-methyl-3,4,4a,5-tetrahydro-1H-pyrazino[1,2-a]qui...)
Affinity DataKi:  600nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2A receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309336(9-methyl-3,4,4a,5-tetrahydro-1H-pyrazino[1,2-a]qui...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in HEK293E cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309336(9-methyl-3,4,4a,5-tetrahydro-1H-pyrazino[1,2-a]qui...)
Affinity DataEC50:  34nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in HEK293E cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309336(9-methyl-3,4,4a,5-tetrahydro-1H-pyrazino[1,2-a]qui...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in HEK293E cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed