BDBM50309513 2-(2,3-difluorophenoxy)-3-(piperidin-4-yl)pyridine::CHEMBL611677

SMILES Fc1cccc(Oc2ncccc2C2CCNCC2)c1F

InChI Key InChIKey=YTQLIVFAWSALJC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50309513   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50309513(2-(2,3-difluorophenoxy)-3-(piperidin-4-yl)pyridine...)
Affinity DataKi:  109nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50309513(2-(2,3-difluorophenoxy)-3-(piperidin-4-yl)pyridine...)
Affinity DataKi:  173nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniquesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50309513(2-(2,3-difluorophenoxy)-3-(piperidin-4-yl)pyridine...)
Affinity DataKi:  1.81E+3nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50309513(2-(2,3-difluorophenoxy)-3-(piperidin-4-yl)pyridine...)
Affinity DataKi: >6.65E+3nMAssay Description:Displacement of [3H]WIN35428 from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed